姓名：吴新鑫
职称：副教授
联系方式：[email protected]
2020/01- 至今 成人直播 ，材料与化学化工学部，副教授
2016/11-2019/12 成人直播 ，成人直播 ，博士后，导师：朱晨教授
2016/07-2016/11 扬子江药业集团江苏海岸药业有限公司，高级研究员
2011/09-2016/07 华东理工大学，博士，制药工程，导师：叶金星教授
2007/09-2011/07 南京工业大学，学士，制药工程
2020年1月以成人直播 “优秀青年学者”身份加盟成人直播 材化学部有机化学系开展教学科研工作，任副教授、硕士生导师。课题组主要从事自由基化学的方法学研究及其在生物活性分子合成中的应用。在Acc. Chem. Res., Chem. Soc. Rev., Nat. Commun., Angew. Chem. Int. Ed., ACS Catal., Chem. Sci. 等国际学术刊物上发表学术论文二十余篇。主持国家级、省级自然科学基金、中国博士后面上项目以及特别资助等基金多项。曾获得2024年第一季度威立Wiley中国高贡献作者奖；江苏省教育教学与研究成果奖（4/5）; 苏州市自然科学优秀学术论文；国家级大学生创新创业训练计划项目。任Chinese Chemical Letters青年编委。
教授课程：研究生《理论有机化学》；本科生《有机化学实验》
研究领域：自由基化学，绿色化学，药物化学，高分子化学，计算化学
代表性论文：
1. Xiu Duan,+ Qihao Jin,+ Kaifeng Wang,+ Yifan Sun, Youhao Wei, Zheng Wang, Jiang-Kai Qiu,* Kai Guo,* Xiaoguang Bao,* Xinxin Wu*. Copper-Catalyzed Site-Selective C(sp2)−H Alkynylation of Allenes. ACS Catal. 2024, 14, 13219-13226.
2. Huiying Liu,+ Zhongtian Wu,+ Haotian Li, Xinxin Wu*. Cu-Catalyzed Regioselective Heteroarylation of C(sp³)—H Bond Induce by Sulfonyl Group. Chin. J. Org. Chem. 2025, 45, 297-306.
3. Qi Zhang,+ Zhongtian Wu,+ Yifan Sun,+ Xiancheng Qiu, Huiying Liu, Xinxin Wu,* Chen Zhu*. Leveraging Propargyl Sulfides as Radical Trappers for the Synthesis of Sulfonyl Allenes. Eur. J. Org. Chem. 2024, 27, e202400364.
4. Rui Fu,+ Mengyu Xu+, Yujing Wang, Xinxin Wu,* and Xiaoguang Bao*. Organo-Photocatalytic Anti-Markovnikov Hydroamidation of Alkenes with Sulfonyl Azides: A Combined Experimental and Computational Study. Angew. Chem. Int. Ed. 2024, 63, e202406069.
5. Youhao Wei+, Zheng Wang+, Kaifeng Wang+, Jiang-Kai Qiu,* Zhaoshan Wang, Haotian Li, Xiu Duan, Kai Guo, Xiaoguang Bao,* and Xinxin Wu*. Copper-catalyzed radical allene C(sp2)-H cyanation. Angew. Chem. Int. Ed. 2024, 63, e202317132. (highlighted by Org. Chem. Front., 2024,11, 2108-2111)
6. Huiying Liu+, Qihao Jin+, and Xinxin Wu*. Intramolecular Hydrogen Atom Transfer from Unactivated C(sp3)-H Bond to Alkyl Radical. Eur. J. Org. Chem. 2024, 27, e202301280. (有机自由基化学专辑邀请文章)
7. Haotian Li,‡ Xiancheng Qiu,‡ Xu Zhang, and Xinxin Wu*. Sulfonyl group-induced remote C(sp3)−N bond construction through hydrogen atom transfer. Org. Lett. 2023, 25, 8814−8818.(Featured in Org. Chem. Highlights)
8. Canxiang Liu, Tingting Feng, Xinxin Wu,* and Chen Zhu*. Fe-catalyzed regioselective C(sp3)−H-abstraction by tertiary cyclopropyl radicals. ACS Catal. 2023, 13, 8394−8401.
9. Tingting Feng, Canxiang Liu, Xinxin Wu*, and Chen Zhu*. Redox-neutral manganese-catalyzed synthesis of 1-pyrrolines Chem. Sci.2022, 13, 2669–2673.
10. Xinxin Wu, and Chen Zhu*. Combination of radical functional group migration (FGM) and hydrogen atom transfer (HAT). Trends in Chemistry, 2022, 4, 580-583.
11. Xinxin Wu, Zhigang Ma, Tingting Feng, and Chen Zhu*. Radical-mediated rearrangements: past, present, and future. Chem. Soc. Rev.2021, 50, 11577–11613.
12. Xinxin Wu, and Chen Zhu*. Radical Functionalization of Remote C(sp3)–H Bonds Mediated by Unprotected Alcohols and Amides. CCS Chem.2020, 2, 813–828.
13. Xinxin Wu, and Chen Zhu*. Radical-Mediated Remote Functional Group Migration. Acc. Chem. Res.2020, 53, 1620-1636.
14. Xinxin Wu†, Mingyang Wang†, Leitao Huan, Dongping Wang, Jinwei Wang, and Chen Zhu*. Tertiary-Alcohol-Directed Functionalization of Remote C(sp3)-H Bonds by Sequential Hydrogen Atom and Heteroaryl Migrations. Angew. Chem. Int. Ed. 2018, 57, 1640-1644. (†co-first author)
15. Xinxin Wu, Hong Zhang, Nana Tang, Zhen Wu, Dongping Wang, Meishan Ji, Yan Xu, Min Wang, Chen Zhu*. Metal-free alcohol-directed regioselective heteroarylation of remote unactivated C(sp3)-H bonds. Nature Communications, 2018, 9, 3343.
16. Shuo Wu†, Xinxin Wu†, Dongping Wang, and Chen Zhu*. Regioselective Vinylation of Remote Unactivated C(sp3)-H Bonds: Access to Complex Fluoroalkylated Alkenes. Angew. Chem. Int. Ed.2019, 58, 1499-1503. (†co-first author)
17. Nana Tang†, Xinxin Wu†, and Chen Zhu*. Practical, Metal-free Remote Heteroarylation of Amides via Unactivated C(sp3)-H Bond Functionalization. Chem. Sci., 2019, 10, 6915-6919. (†co-first author)
18. Xinxin Wu, and Chen Zhu*. Radical Functionalization of Remote C(sp3)-H Bonds Mediated by Unprotected Alcohols and Amides. CCS Chem.2020, 2, 813-828.
19. Xinxin Wu, and Chen Zhu*. Recent Advances in Alkoxy Radical-promoted C-C and C-H Bond Functionalization Starting from Free Alcohols. Chem. Commun.2019, 55, 9747-9756.
20. Xinxin Wu, and Chen Zhu*. Recent Advances in Radical-Mediated C-C Bond Fragmentation of Non-Strained Molecules. Chin. J. Chem.2019, 37, 171-182.
21. Xinxin Wu, and Chen Zhu*. Recent Advances in Ring-Opening Functionalization of Cycloalkanols by C-C s-Bond Cleavage. Chem. Rec.2018, 18, 587-598.
22. Xinxin Wu, Shuo Wu, and Chen Zhu*. Radical-mediated Difunctionalization of Unactivated Alkenes through Distal Migration of Functional Groups. Tetrahedron Lett.2018, 59, 1328-1336.
23. Xinxin Wu, Chunna Meng, Xiaoqian Yuan, Xiaotong Jia, Xuhong Qian, and Jinxing Ye*. Transition-metal-free Visible-light Photoredox Catalysis at Room-temperature for Decarboxylative Fluorination of Aliphatic Carboxylic Acids by Organic Dyes. Chem. Commun.2015, 51, 11864-11867.
